Dr. Holloway is a Professor of Medical and Clinical Psychology and Psychiatry at Uniformed Services University of the Health Sciences, a Diplomate of the Academy of Cognitive Therapy, and Faculty Speaker for the Beck Institute. She completed her postdoctoral training at the University of Pennsylvania under the mentorship of Dr. Aaron T. Beck. As the Founder and Director for the Suicide Care, Prevention and Research Initiative, Dr. Holloway has served as a Principal Investigator on studies funded by the Brain and Behavior Research Foundation, Congressionally Directed Medical Research Program, Defense Suicide Prevention Office, Military Operational Medicine Research Program, Military Suicide Research Consortium, the U.S. Air Force, Marine Corps, Navy, and Special Operations Command.

Dr. Holloway has served as a member of the Defense Health Board Task Force and the Chair of the NATO Research Task Group on military suicide prevention. She has developed and disseminated a number of evidence-informed psychosocial programs for the prevention of suicide including the Air Force Guide for Suicide Risk, the Chaplains-CARE program, Special Operations Cognitive Agility Training, and Post-Admission Cognitive Therapy for inpatient psychiatric care. Dr. Holloway maintained a private clinical practice for 15 years, shifting recently to a consulting practice.